be made in：在……地方制造；be made of：由…制成。be made in：in表示“在里面”的静止状态或一定范围内的动作；be made of：of是英语中一个常用的介词，助动词，表示……的；由…制成等意思，在英语中有大量词组使用of，如out of由于。

This kind of decision cannot ever be made in a vacuum.

这种决定绝不能脱离实际。

Cancellations must be made in writing.

撤销必须有书面通知。

Progress on this issue must be made in parallel to any moves on the economic front.

这个问题上的进展应该和经济领域的进展同步。

Good studies are needed to lend credence to the notion that genuine progress can be made in this important field.

需要进行认真的研究，以让人们相信在这一重要领域可以取得真正的进展。

The pipes should be made of plastic.

这些管子应该是用塑料制作的。

The taps appeared to be made of solid gold.

水龙头似乎是用纯金制成的。

Only the rough guess and estimate can be made of it.

对此只能作出一个粗略的测算。

Everybody should be made aware of the risks involved.

应该让人人都知道其中的风险。

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